Pimasertib and Serous Retinal Detachments

نویسندگان

  • Alaa AlAli
  • Ahmad Bushehri
  • Jonathan C. Park
  • Hatem Krema
  • Wai-Ching Lam
چکیده

PURPOSE To report a case of multifocal serous retinal detachments associated with pimasertib. METHODS The authors report a 26-year-old patient who developed bilateral multifocal serous retinal detachments appearing 2 days after starting pimasertib (as part of a clinical trial investigating its use in low-grade metastatic ovarian cancer) and rapidly resolving 3 days after stopping it. CONCLUSION The mechanism of MEK inhibitor induced visual toxicity remains unclear. The pathophysiology of multifocal serous retinal detachments as a complication of pimasertib is still poorly understood.

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عنوان ژورنال:

دوره 10  شماره 

صفحات  -

تاریخ انتشار 2016